过刊浏览

大鼠鞘内注射多巴胺受体激动剂与拮抗剂对痛及针刺镇痛的影响

摘要

在正常清醒大鼠,it D_(2)受体选择性激动剂LY171555(LY)或D_(1)/D_(2)受体流动剂阿朴吗啡(APO)有镇痛作用(呈剂量依赖式增加),并加强AA,而it D_(1)受体选择性激动剂SKF38393(SKF)对痛及AA均无影响;it D_(1)受体选择性拮抗剂SCH23390(SCH)或D_(2)受体选择性拮抗剂舒必利(Sul)均减弱AA的效应。

关键词： 多巴胺受体; 针刺镇痛; 鞘内注射; 阿朴吗啡; SKF38393; LY171555; 舒必利; SCH23390

Effect of intrathecal injection of dopamine agonists/antagonists on pain and acupucture analgesia in rats

Abstract

Key words: Dopamine receptor;Acupuncture analgesia;Intrathecal administration;Apomorphine;SKF38393;LY171555;Sulpiride;SCH23390

收稿日期：　　录用日期：

通讯作者：　　E-mail:

引用本文：

. 大鼠鞘内注射多巴胺受体激动剂与拮抗剂对痛及针刺镇痛的影响[J]. 生理学报 1998; 50 (1): .

. Effect of intrathecal injection of dopamine agonists/antagonists on pain and acupucture analgesia in rats. Acta Physiol Sin 1998; 50 (1): (in Chinese with English abstract).