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大鼠脊髓α_(1)肾上腺素受体参与延髓腹面升压区调控肾交感神经电活动

林默君, 贾秉钧

福建医学院生理学教研室

摘要

向大鼠脊髓下胸段蛛网膜下腔注射6-羟多巴胺预处理后, 刺激延髓腹面升压区(VSMp)诱发肾交感神经电活动(RSNA)的增强被取消, 平均动脉压(MAP)的提升明显被抑制; 蛛网膜下腔注 射苯肾上腺素所诱发的MAP、RSNA增强效应不受影响。结果提示参与介导VSMp下行性兴奋的 脊髓α_(1)肾上腺素受体位于交感节前神经元的突触后。图3表1参7

关键词： 延髓腹面升压区; 交感节前神经元; α_(1)肾上腺素受体; 6-羟多巴胺; 苯肾上腺素

#alpha#_(1)adrenoceptor involved in the process of VSMp control of renal sympathetic nerve activities in spinal cord on rats

Lin Mojun, Jia Bingjun

Dept. Physiol., Fujian Med. Coll.

Abstract

Key words: Pressor area of ventral surface of medulla;Sympathetic preganglionic neuron;#alpha#_(1)-adrenoceptor;6-hydroxydopamine;Phenylephrine

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引用本文：

林默君, 贾秉钧. 大鼠脊髓α_(1)肾上腺素受体参与延髓腹面升压区调控肾交感神经电活动[J]. 生理学报 1993; 45 (6): .

Lin Mojun, Jia Bingjun. #alpha#_(1)adrenoceptor involved in the process of VSMp control of renal sympathetic nerve activities in spinal cord on rats. Acta Physiol Sin 1993; 45 (6): (in Chinese with English abstract).