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人肝刺激因子对CC_(14)损伤大鼠离体肝细胞内钙和钾离子稳态的影响

邵青, 梅懋华

大连医学院生理教研室

摘要

人胎肝中含有人肝刺激因子(hHSS),hHSS能提高离体肝细胞的存活率,维持肝细胞内游离钙的相对恒定,减少细胞内钾离子和转氨酶的漏出。提示hHS S可保护肝细胞内钙、钾离子稳态和 肝细胞膜的稳定,从而加强大鼠离体肝细胞抗CC_(l4)的损伤。图3表1参22

关键词： 人肝刺激因子; 四氯化碳; 钙; 钾; 转氨酶; 肝细胞保护

Effect of human hepatic stimulator substance on intracellular calcium and potassium homeostasis in CC_(14)-intoxication dissociated hepatocytes

Shao Qing, Mei Maohua

Dept.Physiol.,Dalian Med.Coll.

Abstract

Key words: Human hepatic stimulator substance (hHSS);Carbon tetrachloride [CC1_(4)];Calcium;Potassium;Alanine transaminase (ALT);Hepatocyte protection

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引用本文：

邵青, 梅懋华. 人肝刺激因子对CC_(14)损伤大鼠离体肝细胞内钙和钾离子稳态的影响[J]. 生理学报 1993; 45 (4): .

Shao Qing, Mei Maohua. Effect of human hepatic stimulator substance on intracellular calcium and potassium homeostasis in CC_(14)-intoxication dissociated hepatocytes. Acta Physiol Sin 1993; 45 (4): (in Chinese with English abstract).