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缰核内注射Ca~(2+)拮抗电针镇痛的作用可被三碘季铵酚翻转

潘玉贞, 王丽华, 唐毓环, 尹宪明, 王绍

白求恩医科大学生理教研室

摘要

通过埋植套管向大鼠双侧缰核分别注射0.1mol/L CaCl_(2)0.5μl、0.06mol/L ACh 0.5 μl、5.4×10~(-3)mol/L三碘季铵酚0.5μl和14.4×10~(-3)mol/L阿托品0.5μl后观察到, Ca~(2+)降低基础痛阈并拮抗电针镇痛效应; ACh拮抗电针镇痛; Ca~(2+)拮抗 电针镇痛的作用可被胆碱能N受体阻断剂三碘季铵酚完全翻转。提示缰核内的Ca~(2+)可 能通过ACh实现其拮抗电针镇痛的效应。图3参18

关键词： 缰核; 电针镇痛; 氯化钙; 乙酰胆碱; 三碘季铵酚; 阿托品

Antagonistic effect of electro-acupuncture analgesia with Ca~(2+) injection into habenula could be reversed by gallamine triethiodide

Pan Yuzhen, Wang Lihua, Tang Yuhuan, Yin Xianming, Wang Shao

Dept. Physiol., N. Bethune Univ. Med. Sci.

Abstract

Key words: Habenula;Electro-acupuncture analgesia;Calcium chloride;Acetylcholine;Gallamine triethiodide;Atropine

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引用本文：

潘玉贞, 王丽华, 唐毓环, 尹宪明, 王绍. 缰核内注射Ca~(2+)拮抗电针镇痛的作用可被三碘季铵酚翻转[J]. 生理学报 1992; 44 (4): .

Pan Yuzhen, Wang Lihua, Tang Yuhuan, Yin Xianming, Wang Shao. Antagonistic effect of electro-acupuncture analgesia with Ca~(2+) injection into habenula could be reversed by gallamine triethiodide. Acta Physiol Sin 1992; 44 (4): (in Chinese with English abstract).