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头端延髓腹外侧区注射5-羟色胺对应激性高血粘度及血压升高的影响

翁可, 郭学勤, 梁子钧

温州医学院生理教研室；上海医科大学生理学教研室；上海医科大学生物物理学教研室

摘要

大鼠第四脑室注射5-羟色胺(5-HT 25μg/10μl)或在双侧延髓腹外侧区头端(rVLM)微量注射5-HT(4μg/0.5μl/每侧)均可抑制应激性高血粘度和血压升高, 若预先在双侧rVLM微量注射5-HT受体阻断剂肉桂硫胺(4μg/0.5μl/每侧)后再在第四脑室或延髓腹外侧区内注入上述同剂量的5-HT, 则5-HT降低应激性高血粘度和血压升高的作用消失。图5表2参18

关键词： 应激; 5-羟色胺; 肉桂硫胺; 头端延髓腹外侧区; 血贴度

Microinjection of 5-HT into the rostral ventrolateral medulla reduced the hyperviscosity and elevation of blood pressure induced by stress

Weng Ke, Guo Xueqin, Liang Zijun

Dept. Physiol., Wenzhou Med. Coll.

Abstract

Key words: Stress;Serotoain;Cinanserine;Rostral ventrolateral medulls;Viscoolty

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引用本文：

翁可, 郭学勤, 梁子钧. 头端延髓腹外侧区注射5-羟色胺对应激性高血粘度及血压升高的影响[J]. 生理学报 1992; 44 (3): .

Weng Ke, Guo Xueqin, Liang Zijun. Microinjection of 5-HT into the rostral ventrolateral medulla reduced the hyperviscosity and elevation of blood pressure induced by stress. Acta Physiol Sin 1992; 44 (3): (in Chinese with English abstract).