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Baduanjin improves sleep quality in patients with type 2 diabetes possibly via regulating Bmal1 gene

DONG Zi-Xuan, MA Zhan-Ke^*

Institute of Physical Education, Ningxia Normal University, Guyuan 756099, China

Abstract

The incidence of diabetes mellitus is increasing, and the sleep quality of patients with diabetes mellitus is often affected. Baduanjin may act on biological rhythm of the body, skeletal muscle glucose metabolism, skeletal muscle fibers and suprachiasmatic nucleus (SCN) by regulating the expression of Bmal1 gene, thus regulating the blood glucose level and circadian rhythm of patients with type 2 diabetes mellitus (T2DM) and improving their physiological functions. This article reviews the regulatory effect and mechanism of Baduanjin on Bmal1 gene expression in diabetes patients, and discusses the possibility of Baduanjin to improve the sleep quality of T2DM patients by regulating Bmal1 gene expression. This review can provide a new field for the clinical application of traditional Chinese Qigong Baduanjin, and provide a new scientific basis for exercise therapy of diabetes.

Key words: Baduanjin; Bmal1; diabetes mellitus; sleep quality

Received: 　　Accepted:

Corresponding author: 马占科　　E-mail:

DOI: 10.13294/j.aps.2024.0046

Citing This Article：

DONG Zi-Xuan, MA Zhan-Ke. Baduanjin improves sleep quality in patients with type 2 diabetes possibly via regulating Bmal1 gene. Acta Physiol Sin 2024; 76 (3): 447-456 (in Chinese with English abstract).