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Research progress on muscle spindle morphology

LIAN Wen-Xi¹, RAO Jia-Sheng¹, HAO Liu-Fang², WANG Zi-Jue², DUAN Hong-Mei², YANG Zhao-Yang², LI Xiao-Guang^1,2,*

¹Beijing Key Laboratory for Biomaterials and Neural Regeneration, School of Biological Science and Medical Engineering, Beihang University, Beijing 100083, China；²Department of Neurobiology, Capital Medical University, Beijing 100069, China

Abstract

Muscle spindle is the key proprioceptor in skeletal muscles and plays important roles in many physiological activities, such as maintaining posture, regulating movement and controlling speed variation. It has significant clinical relevance and is emerging as a promising therapeutic target for the treatment of motor functional impairment and metabolic diseases. In this review, we summarized muscle spindle distribution and the mechanism of mechanical signal transmission, and reviewed the research progress on morphological and structural characteristics of muscle spindles.

Key words: muscle spindle; morphology; satellite cell; Schwann cell; fibro/adipogenic progenitor

Received: 　　Accepted:

Corresponding author: 李晓光　　E-mail: lxgchina@sina.com

Citing This Article：

LIAN Wen-Xi, RAO Jia-Sheng, HAO Liu-Fang, WANG Zi-Jue, DUAN Hong-Mei, YANG Zhao-Yang, LI Xiao-Guang. Research progress on muscle spindle morphology. Acta Physiol Sin 2022; 74 (6): 1039-1047 (in Chinese with English abstract).