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Research progress in process and mechanisms of embryo implantation

XU Qi-Xin, SU Ren-Wei^*

College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China

Abstract

The onset of tight connection between embryo and uterine endometrium terms “embryo implantation”, the beginning and a key step of mammalian pregnancy. Defective implantation leads to failure of pregnancy and infertility. In recent years, along with the technological advance, researches on embryo implantation have achieved great advances. This paper reviews the key research achievements that have been reached in the last decade in the field of embryo implantation, focusing on the changes, roles, and underlying mechanisms of both luminal and glandular epithelia during implantation process, as well as their interactions with embryo trophoblast cells and endometrial stromal cells.

Key words: embryo implantation; uterine endometrium; luminal cell polarity; uterine glands

Received: 2019-07-13　　Accepted: 2019-09-22

Corresponding author: 苏仁伟　　E-mail: renweisu@scau.edu.cn

DOI: 10.13294/j.aps.2020.0004

Citing This Article：

XU Qi-Xin, SU Ren-Wei. Research progress in process and mechanisms of embryo implantation. Acta Physiol Sin 2020; 72 (1): 91-104 (in Chinese with English abstract).