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Advance in effect of aerobic exercise on immune system and autoimmune diseases

XIE Yu^1,2,3, WANG Jun-Peng^1,3,*

¹Translational Medical Center of Huaihe Hospital, Henan University, Kaifeng 475000, China；²College of Physical Education, Henan University, Kaifeng 475000, China；³Institute of Infection and Immunity, Henan University, Kaifeng 475000, China

Abstract

Autoimmune diseases are a kind of chronic diseases with unclear etiology, which has the characteristics of repetition and difficulty to cure completely. Aerobic exercise, as an effective intervention method for chronic diseases, has also received extensive attention in the field of the prevention and treatment of autoimmune diseases. In this paper, the effects of aerobic exercise on immune system and autoimmune diseases in recent years are reviewed, and the related mechanisms are discussed. It is pointed out that aerobic exercise can improve the homeostasis of immune environment by affecting the number and function of immune cells, inhibit the systemic inflammatory response of the body, and then delay the occurrence and development of autoimmune diseases. 

Key words: aerobic exercise; immunity; autoimmune diseases; inflammation

Received: 2019-02-21　　Accepted: 2019-05-14

Corresponding author: 王军朋　　E-mail: jpwangchina@henu.edu.cn

DOI: 10.13294/j.aps.2019.0062

Citing This Article：

XIE Yu, WANG Jun-Peng. Advance in effect of aerobic exercise on immune system and autoimmune diseases. Acta Physiol Sin 2019; 71 (5): 769-782 (in Chinese with English abstract).