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Insulin and cardiovascular protection: from bench to bedside

ZHANG Hai-Feng¹, ZHANG Xing², Gao Feng^2,*

¹Experimental Teaching Center, The Fourth Military Medical University, Xi’an 710032, China；²Department of Aerospace Medicine, The Fourth Military Medical University, Xi’an 710032, China

Abstract

 Insulin resistance is “common soil” of many major cardiovascular diseases, such as diabetes, coronary heart disease, hypertension and heart failure. Recent studies have revealed that, in addition to metabolic modulation, insulin exerts direct cardiovascular protective effects. This article reviews the current progresses in the pathogenesis and cardiovascular protection strategies of metabolic cardiovascular diseases, and highlights the mechanism of actions of insulin in cardiovascular protection.

Key words: cardiovascular protection;;;;

Received: 2017-07-24　　Accepted: 2018-01-11

Corresponding author: 高峰　　E-mail: fgao@fmmu.edu.cn

DOI: 10.13294/j.aps.2018.0005

Citing This Article：

ZHANG Hai-Feng, ZHANG Xing, Gao Feng. Insulin and cardiovascular protection: from bench to bedside. Acta Physiol Sin 2018; 70 (1): 61-70 (in Chinese with English abstract).