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[Fat mass and fat free mass on ventilatory function in adults.] [Ariticle in Chinese]

FENG Kui, CHEN Li, ZU Shu-Yu, HAN Shao-Mei, ZHU Guang-Jin

Department of Physiology and Pathophysiology； Department of Epidemiology and Statistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100005, China

Abstract

This study is designed to probe for the effects of fat mass (FM) and fat free mass (FFM) on ventilatory function in adults.1 307 healthy adults (372 males and 935 females) were selected from some localities of Heilongjiang province through random samplingby means of questionnaire and physical examination and measured for height, weight, waist to hip ratio (WHR), FM, FFM andventilatory function. The data were analyzed by means of Pearson correlation analysis, independent-samples t test and multi-factorsregression analysis. Regardless of sex, an independent positive correlation was found (P<0.001) between age and fat mass index (FMI).Regardless of sex, fat free mass index (FFMI) was found to be positively associated with forced vital capacity (FVC), forced expiratoryvolume in one second (FEV1), peak expiratory flow (PEF) and forced expiratory flow at 25% of forced vital capacity (FEF25%) (P<0.01), and FMI was significantly and negatively related to FVC, FEV1, FEF75% (P<0.05). In males FMI was significantly andnegatively related to maximal mid-expiratory flow (MMEF) (P<0.05). Regardless of sex, the effect of FFMI on FVC was higher thanthat of FMI. For the males, the effect of FFMI on FVC was smaller than that of FMI, while the opposite was found in the females.Regardless of sex, FEF75% tended to decrease with increasing FMI, while FFMI was found to have no effects on FEF75%. MMEFtended to decrease with increasing FMI in the males, but no marked change was found in the females. The above results suggest that FMand FFM are independent factors influencing ventilatory function in adults. FM is negatively correlated with ventilatory function, butas a reflection of muscle mass, FFM is positively correlated with ventilatory function in adults. There is quantitative difference between the effects of FFM and FM on ventilatory function.

Key words: body composition; forced expiratory flow rates; forced vital capacity

Received: 2009-11-13　　Accepted: 2010-01-19

Corresponding author: 朱广瑾　　E-mail: zhugj@pumc.edu.cn

Citing This Article：

FENG Kui, CHEN Li, ZU Shu-Yu, HAN Shao-Mei, ZHU Guang-Jin. [Fat mass and fat free mass on ventilatory function in adults.] [Ariticle in Chinese] . Acta Physiol Sin 2010; 62 (2): 122-128 (in Chinese with English abstract).