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Effect of high altitude hypoxia on fetal development during pregnancy and the reason analysis

LIU Juan-Li, MA Si-Qing, WUREN Ta-Na

Department of Critical Care Medicine, Qinghai Provincial People’s Hospital, Xining 810007, China； Plateau Medical Center of Qinghai University, Xining 810001, China

Abstract

High altitude hypoxia is an important factor to affect fetal development during pregnancy. In the special environment, maternal physiological functions are regulated to maintain the maternal and fetal homeostasis, so that limited oxygen is to meet the needs of fetal growth and development. In this review, the literatures about the effects of hypoxic environment on fetal development during pregnancy in recent years were summarized, in which the fetal growth characteristics, maternal physiological regulation, genetic and placental influencing factors in high altitude areas were involved. This may be helpful for the reproductive healthcare of women in high altitude region, and also for the treatment and prevention of fetal growth retardation in the hypoxic environment.

Key words: high altitude; hypoxia ; fetus during pregnancy ; influences ;

Received: 2016-08-04　　Accepted: 2016-11-15

Corresponding author: 马四清　　E-mail: siqing177@sina.com

Citing This Article：

LIU Juan-Li, MA Si-Qing, WUREN Ta-Na. Effect of high altitude hypoxia on fetal development during pregnancy and the reason analysis. Acta Physiol Sin 2017; 69 (2): 235-239 (in Chinese with English abstract).