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[An efficient way in mouse brain dissection.] [Article in Chinese]

WANG Jin-Zhao, LONG Cheng, YANG Li

School of Life Sciences； School of Psychology, South China Normal University, Guangzhou 510631, China

Abstract

Laboratory mice are common experimental animals in biological, medical, pharmacological and psychological researches primarily because they are easy to maintain and reproduce quickly. The protection of the welfare of experimental animals is gaining greater attention during the application of a large number of mice. It's therefore essential to consider how to reduce the unnecessary use of animals and fully exploit each experimental animal. We report, in this article, an efficient way to dissect various brain regions from a mouse for protein immunoblot and/or neuronal culture, providing technical reference information for minimizing the number of animals used in projects, and refining methods and procedures to quick brain dissection.

Key words: Hippocampus; cortex; striatum; olfactory bulb; brain dissection method

Received: 2013-07-06　　Accepted: 2013-10-30

Corresponding author: 杨莉　　E-mail: yangli08@scnu.edu.cn

Citing This Article：

WANG Jin-Zhao, LONG Cheng, YANG Li. [An efficient way in mouse brain dissection.] [Article in Chinese]. Acta Physiol Sin 2014; 66 (2): 210-214 (in Chinese with English abstract).