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Optimal pulmonary ventilation determined by the relation between end-tidal CO2 and arterial blood pressure in artificially respirated cat

LI CHAO-YI

Shanghai Institute of Physiology, Chinese Academy of Sciences, Shanghai 200031, China

Abstract

End-tidal CO2 (ET-CO2) provides a continuous and sensitive monitoring of proper pulmonary ventilation in artificially ventilated animals during single unit recordings of the central nervous system. To determine a reliable standard of ET-CO2 in anesthetized and paralyzed animal, the relationship between ET-CO2 and arterial blood pressure (ABP) was observed in cat under different ventilation level. The results showed that ABP changed tremendously with variation in ventilation, but remained constant at a normal level as long as ET-CO2 was maintained within the range between 4.0-5.0%, i.e. optimally at 4.5 +/- 0.5%.

Key words: Cat; arterial blood pressure; pulmonary ventilation; artificial respiration; carbon dioxide

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Citing This Article：

LI CHAO-YI. Optimal pulmonary ventilation determined by the relation between end-tidal CO2 and arterial blood pressure in artificially respirated cat. Acta Physiol Sin 1992; 44 (6): 597-602 (in Chinese with English abstract).