Issue Archive

Cui Hong

First Clinical Institute，China Medical University. Shenyang 110001,Liaoning, China

Abstract

Electrophysiological properties, reaction to sustance P (SP) receptor agonist, and co-existence of glutamate (Glu) and SP in neurons of the spinal dorsal root ganglion (DRG) of the rat were investigated in vitro.The main results were: (1) According to the fiber conduction velocity, totally 135 intracellularly recorded DRG neurons were divided into Aα/β type(> 12m/s) and C type (<1.3 m/s). There were remarkable differences between the fast afterhyperpolarization (fAHP) of action potential between the two types:fAHP of C type neurons had smaller amplititude and longer duration, whereas the fAHP of Aα/β type neurons had larger amplititude and: shorter duration. (2) Among 22 DRG neurons of which overshoots of action. protential appeared, specific SP receptor agonist Sar-SP induced depolorization in 42% (5/12) of the Aα/β type neurons and 80% (8/10)of the C type neurons. (3) Biocytin was intracellularly injected into the 22 Sar-SP administrated DRG neurons.

Key words: ;;;;;

Received: 　　Accepted:

Corresponding author: 　　E-mail:

Citing This Article：

Cui Hong. . Acta Physiol Sin 1998; 50 (4): (in Chinese with English abstract).