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Cui Hong

First Clinical Institute，China Medical University. Shenyang 110001,Liaoning, China

Abstract

The effects of adenosine (Ado) on the carotid barewhex were studied in 27 anesthetized rats with isolated caretid sinus pemision. The restilts obtained were as follows: (1) By perfusing the isolated carotid sinus with adenosine (125 μmol/L), the functional curve of bamreflex was shifted to the left and downward, with the peak slope (PS) increased from 0.37±0.02 to 0.55±0.02 kPa/kPa (P<0.001) and the reflex decrease in mean alienal pressure (RD) enhanced from 5. 53±0.12 to 7 .76±0. 36 kPa (P<0.001). Meanwhile, the theshold pressure (TP), eqUilibrium pressure (EP) and saturation pressure (SP) were significantly decreased from 8. 60±0 .27 to 5. 63±0. 11 kPa (P<0.001), 12.53±0.30 to 10.89±0.29 kPa (P<0.01) and 23.69±0. 15 to 20. 18±0.55 kPa (P<0.001), respectively. Among the functional parameters of camtid hamreflex I the changes of RD,PS and TP induced by Ado were dose-dependent.

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Citing This Article：

Cui Hong. . Acta Physiol Sin 1998; 50 (3): (in Chinese with English abstract).