Issue Archive

Effect of stimulation of dorsal raphe nucleus on activities of purkinje in cerebellar cortex of the cat

Wu Min, Chen Jun, Yu Qixiang

Division of Physiology, Department of Biology, Nanjing University. Nanjing 210008, China

Abstract

The effect of stimulation of peripheral nerves and dorsal raphe nucleus on
activities of the cerebellar Purkinje cells (PC) in cats was studied. The experiments were performed on the decerebrate, unanesthetized cats. The changes in PC activity after stimulation of nervi peronaeus profundus (NPP) and nervi radilis profundus (NRP) were recorded, and the influence of raphe stimulation on the response of PC to peripheral inputs and on spontaneous activity of PC
were examined. The discharges in 38% PC of lobule A and 52% PC of lobule
Vwere either increased or depressed by NPP stimulation. The excitability of 27% PC in lobule AA was also changed following NRP stimulation. The response of PC to the raphe stimulation was mainly inhibitory in nature, i.e.，in 83% of the
cells. This suppressive effect became more marked when peripheral nerves were
stimulated. Possible role of dorsal raphe nucleus on the response of PC to peripheral inputs is discussed.

Key words: Dorsal raphe nucleus;Cerehellar cortex;Purkinje cell;Peripheral nervs stimulation

Received: 　　Accepted:

Corresponding author: 　　E-mail:

Citing This Article：

Wu Min, Chen Jun, Yu Qixiang. Effect of stimulation of dorsal raphe nucleus on activities of purkinje in cerebellar cortex of the cat. Acta Physiol Sin 1987; 39 (5): (in Chinese with English abstract).