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Studies on the spontaneous contraction and the response to ne of isolated oviductal isthmic muscle from chinese women under different ovarian hormonal states

Yang Lizhen, Hsieh Chungming, Xu Meihong, Yang Aili

Shanghai Institute of Planned Parenthood Research. Shanghai, China

Abstract

Isolated isthmic smooth muscle of different phases(i.e. proliferative,secretory,
menstrual,pregnant and lactating phase)from 58 normal Chinese women(22-40
years old, during salpingectomy for sterilization) was used for the study of contraction and sensitivity of response to norepinephrine (NE) [10~(-7)-10~(-3) mol/L accumulative concentration). Isthmic smooth muscle activities at proliferative, menstrual and lactating phases were stronger and at a higher frequency than those at secretory and pregnant phases.The response of the isthmic smooth muscle to NE at proliferative, menstrual,secretory and lactating phases is excitatory in nature, while that at pregnant phase is inhibitory. The result also shows that the contractility of circular muscle is stronger than that of longitudinal muscle but of similar contractile pattern.

Key words: Oviductal smooth muscle;Spontaneous contraction;Norepinephrine;Differetn ovarian hormonal states

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Citing This Article：

Yang Lizhen, Hsieh Chungming, Xu Meihong, Yang Aili. Studies on the spontaneous contraction and the response to ne of isolated oviductal isthmic muscle from chinese women under different ovarian hormonal states. Acta Physiol Sin 1987; 39 (4): (in Chinese with English abstract).