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Role of hypoxia-inducible factor-1α in the prevention of cardiomyocyte injury induced by hypoxic preconditioning

Xu Feifei, Liu Xiuhua, Cai Lirong

Department of Pathophysiology, Chinese PLA General Hospital. Beijing 100853, China

Abstract

In order to understand the intracellular mechanism of preconditionint, we investigated the relationship among activities of extracellular signal-regulated protein kinases (ERKs), the expression of hypoxia-inducible factor-1 #alpha# (HIF-1 #alpha#) and the effect of hypoxic preconditionint (HPC) on the cell injury induced by hypoxia-reoxygenation in cultured neonatal rat cardiomyocytes 24 h after brief hypoxia;

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Citing This Article：

Xu Feifei, Liu Xiuhua, Cai Lirong. Role of hypoxia-inducible factor-1α in the prevention of cardiomyocyte injury induced by hypoxic preconditioning. Acta Physiol Sin 2004; 56 (5): (in Chinese with English abstract).