Tutin-induced epileptiform discharge of CA1 pyramidal cells in rat hippocampal slices
Zhou Hua, Zheng Yu, Tangyuong
West China School of Preclinical and Forensic Medicine, Sichuan University. Chengdu 610041, China
Abstract
Previous studies showed that a mixture, Coriaria Lactone (CL), extracted form a traditional Chinese herb Loranthus Parasiticus Mer. had a great excitatory influence on the nervous system, resulting in seizure. But what component in CL causes seizure is unclear. Tutin is a pure chemical component derived form CL. The present experiments were carried out to test if tutin has any epileptogenic action and to preliminarkly study the mechanism underlyint that action in Vitro.
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Citing This Article：
Zhou Hua, Zheng Yu, Tangyuong. Tutin-induced epileptiform discharge of CA1 pyramidal cells in rat hippocampal slices. Acta Physiol Sin 2004; 56 (3): (in Chinese with English abstract).
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