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EFFECTS OF DIFFERENT NATURAL STIMULANTS ON THE ACTIVITY OF THE RABBITS' CAROTID CHEMORECEPTOR

Pang Lei, MIAO ZHI-HUI, WANG YAN-LING , DONG LI

(Department of Physiology, Hebm Academy of Medical Sciences, Shijiazhuang 050021)

Abstract

The effects of different natural stimulants on the afferent unit discharge of rabbit carotid chemoreceptors were studied in the in vitro carotid body- sinus nerve preparation. A total of 32 chemoreceptive units were recorded. The results were as follows:(1)Of the 32 units，10 (31%)showed chemosensory responses only to POZ decrease;9 (28%)to all stimulants (P02 decrease，PC02 increase and pH decrease);9 (280o)to POZ decrease and PC02 increase;3(9%)to PO_(2) decrease and pH decrease;only one to pH decrease. (2) The potency of the three natural stimulants in eliciting the changes in intensity of discharge showed a decreasing order as follows:POZ decrease>PC02
increase>pH decrease. The above results suggest that the carotid body may contain only one or a combination of 2 or 3 kinds of chemoreceptors respectively sensitive to decrease POZ to increase PC0_(2 )or decrease pH.

Key words: PO_(2);PC0_(2);pH;Carotid chemoreceptor;afferent unit discharge

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Citing This Article：

Pang Lei, MIAO ZHI-HUI, WANG YAN-LING , DONG LI. EFFECTS OF DIFFERENT NATURAL STIMULANTS ON THE ACTIVITY OF THE RABBITS' CAROTID CHEMORECEPTOR. Acta Physiol Sin 1996; 48 (6): (in Chinese with English abstract).