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EFFECT OF ACUTE HYPOXIA ON THE CHANGE OF HIPPOCAMPAL NE CONTENT AND PLASMA CORTISOL LEVEL

ZHU XIAO-MAN, GAO YANG, ZHOU WEI-JUN, ZHOU YU-QIAN

Department of Physiology Nanjing Railway Medical College Nanjing 210009)

Abstract

The effect of acute hypoxia on the changes of plasma cortisol level and hippocanr pus NE level of cat during inhalation of 21%，10. 4%or 7. 9%Oz were investigated.It was found that both 10. 4%and 7. 9%OZ inhalation caused a gradual increase in plasma cortisol level reaching a plateau in 30-45 min time. While the contents of NE in VHIP and DRIP showed significant decrease 30 min after hypoxia. The degree of both these changes are not related to the hypoxic level of the inhaled 02. The results show that acute hypoxic stress would induce some increase in plasma cortisol level and some decrease in hippocampus NE content.

Key words: Hypoxia;Cortisol;Norepinephrine;Hippocampus;cat

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Citing This Article：

ZHU XIAO-MAN, GAO YANG, ZHOU WEI-JUN, ZHOU YU-QIAN. EFFECT OF ACUTE HYPOXIA ON THE CHANGE OF HIPPOCAMPAL NE CONTENT AND PLASMA CORTISOL LEVEL. Acta Physiol Sin 1996; 48 (4): (in Chinese with English abstract).