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Effects of genistein on intracellular free-calcium concentration in guinea pig ventricular myocytes

Ji Ensheng, Wang Chuan, He Ruirong

Department of Physiology,Institute of Basic Medicine,Hebei Medical University.Shijiazhuang 050017,Hebei；Department of Physiology,Institute of Basic medicine,Hebei Medical University.Shijiazhuang 050017,Hebei；China

Abstract

These results suggests that GST may reduce the [Ca~(2+)]_(i) in isolated guinea pig ventricular myocytes. The inhibition of voltage-dependent Ca~(2+) channel, tyrosine kinase inhibition, and alleviation of Ca~(2+) release from SR are possibly involved in the GST effect.

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Citing This Article：

Ji Ensheng, Wang Chuan, He Ruirong. Effects of genistein on intracellular free-calcium concentration in guinea pig ventricular myocytes. Acta Physiol Sin 2004; 56 (2): (in Chinese with English abstract).