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A brief introduction to the secretion mechanism in immunocytes

Lou Xuelin, He Liming, Gong Feili, Yu Xiao, Xu Tao, Zhou Zhuan

Institute of Biophysics and Biochemistry,Huazhong University of Science and Technology.Wuhan 430074,Hubei；China；Institute of Neuroscience.Shanghai 200031

Abstract

Exocytosis is a vital function of many cell types including neuron, endocrine cell and immunocyte. Secretion in immunocytes involves a complex process of signal transduction, in which many factors still remain unknown. In the last 10 years, this area has become an international hot spot of investigation, resulting in many break-through progresses. This progress was made possible by combined efforts in molecular biology, cell biology and biophysics. This review focuses on notable new knowledge and some new techniques in functional study of secretion in immunocytes.

Key words: Bodily secretions;Real-time;Cell factor;Soluble NSF attachment protein receptors(SNARE);Fusion pore

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Citing This Article：

Lou Xuelin, He Liming, Gong Feili, Yu Xiao, Xu Tao, Zhou Zhuan. A brief introduction to the secretion mechanism in immunocytes. Acta Physiol Sin 2002; 54 (3): (in Chinese with English abstract).