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Comparison of the electrophysiological features between the rhythmic cells of the aortic vestibule and the sinoatrial node in the rabbit

Zhang Xiaoyun, Chen Yanjing, Ge Fugui, Wang Debao

Department of Physiology,Zhangjiakou Medical College.Zhajiakou 075029,Hebei

Abstract

These results suggested: (1) the ion currents in phase 0 and phase 4 of depolarization and repolarization of slow-response activity in aortic vestibule are similar to those in dominant pacemaker cells of sinoatrial node; (2) for the pacemaker cells in the left ventricular outflow tract, Ca~(2+) current is the main depolarizing ion current of the phase 0, K~(+) current is the main factor responsible for the repolarization. Attenuation of K~(+) current is reponsible for the phase 4 spontaneous depolarization. In addition, it seems that I_(Ca-T), I_(Ca-L) and I_(f) play some role in the pacemaker currents.

Key words: Aortic vestibule;Sinoatrial node;Electrophysiology;Comparative research

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Citing This Article：

Zhang Xiaoyun, Chen Yanjing, Ge Fugui, Wang Debao. Comparison of the electrophysiological features between the rhythmic cells of the aortic vestibule and the sinoatrial node in the rabbit. Acta Physiol Sin 2003; 55 (4): (in Chinese with English abstract).