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17#beta#-Estradiol inhibits vascular smooth muscle cell proliferation and c-fos expression: role of nitric oxide

Yang Dan, Tan Zhi, Liu Peiqing, Pan Jingyun, Wang Tinghuai

Department of Physiology,Sun Yat-sen University of Medical Sciences.Guangzhou 510080,Guangdong

Abstract

Results suggest that the inhibitory effects of E_(2) on VSMC cellular proliferation and c-fos mRNA expression are closely related with NO release in VSMC, which is, at least, partly medicated by ER.

Key words: Vascular smooth muscle cell;Estrogen;Nitric oxide;Nitric oxide synthase

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Citing This Article：

Yang Dan, Tan Zhi, Liu Peiqing, Pan Jingyun, Wang Tinghuai. 17#beta#-Estradiol inhibits vascular smooth muscle cell proliferation and c-fos expression: role of nitric oxide. Acta Physiol Sin 2002; 54 (1): (in Chinese with English abstract).