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Apoptosis during placentation

Gao Fei, Fu Guoqiang, Ding Feng, Liu Yixun

State Key Laboratory of Reproductive Biology,Institute of Zoology,Chinese Academy of Sciences.Beijing 100080

Abstract

Apoptosis is a normal physiological phenomenon. During the process of implantation, there are a large number of cells at the implantation site undergoing apoptosis, which has been suggested to play an important role in the regulation of endometrium decidulization and trophoblast invasion. Apoptosis mediated by Fas/FasL system may also be associated with maternal immunotolerance to the fetus. In this review, the common pathway of apoptosis and the regulation in the placenta are described.

Key words: Apoptosis;Placentation;Immunotole rance;Fas/ FasL

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Citing This Article：

Gao Fei, Fu Guoqiang, Ding Feng, Liu Yixun. Apoptosis during placentation. Acta Physiol Sin 2001; 53 (6): (in Chinese with English abstract).