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Role of nitric oxide in cholecystokinin-octapeptide alleviation of tumor necrosis factor-alpha induced changes in rabbit pulmonary arterial reactivity

Meng Aihong, Ling Yiling, Wang Dianhua, Gu Zhenyong, Li Shujin, Zhu Tienian

Department of Pathophysiology,Hebei Medical University.Shijiazhuang 050017,Hebei

Abstract

Results suggest that CCK-8 prevents TNF-#alpha# induced impairment in endothelium-dependent relaxation response, and the effects of both CCK-8 and TNF-#alpha# are related to NO.

Key words: Cholecystokinixr octapeptide;Tumor necrosis factor alpha;Nitric oxide;Pul monary;Vascular reactivity

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Citing This Article：

Meng Aihong, Ling Yiling, Wang Dianhua, Gu Zhenyong, Li Shujin, Zhu Tienian. Role of nitric oxide in cholecystokinin-octapeptide alleviation of tumor necrosis factor-alpha induced changes in rabbit pulmonary arterial reactivity. Acta Physiol Sin 2001; 53 (6): (in Chinese with English abstract).