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Changes in G#alpha#q/11-mediated signal transduction pathway in the aorta of two kidney one clip hypertensive rats

Xing Dongqi, Bai Hua, Ma Tiemin, Wu Liling

Department of Physiology and Pathophysiology,Peking University Health Science Center.Beijing 100083；China

Abstract

The results indicate that G#alpha#q/11-mediated signal transduction pathway of the aorta is activated in 2K1C hypertension, and may contribute to the initiation and maintenance of renal hypertension.

Key words: Renal hypertension;Gaq/11 protein;Phospholipase C;Extracellular signal-regulated kinase 1/2

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Citing This Article：

Xing Dongqi, Bai Hua, Ma Tiemin, Wu Liling. Changes in G#alpha#q/11-mediated signal transduction pathway in the aorta of two kidney one clip hypertensive rats. Acta Physiol Sin 2001; 53 (6): (in Chinese with English abstract).