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Modification of membrane lipid of human umbilical vein endothelial cells after direct lipopolysaccharide injury

Wang Xiang, Cai Shaoxi, Luo Xiangdong, Wang Pei, Luo Qin, Liang Guangping, Yang Zongcheng

Bioengineering College of Chongqing University,The Open Laboratory for Biomechanics and Biorheology Under the Ministry of Education.Chongqing 400044；China

Abstract

Results indicate that LPS directly activates the metabolism of HUVEC membrane lipid and induces the modification of HUVEC membrane phospholipid, which implies that the mechanism of the impairment of HUVECs by LPS may be related to the membrane structure of HUVECs and the metabolism of HUVEC membrane lipid.

Key words: Lipopolysaccharide(LPS);Direct damage;Human umbilical vein endothelial cell(HUVEC);Modification of membrane lipid

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Citing This Article：

Wang Xiang, Cai Shaoxi, Luo Xiangdong, Wang Pei, Luo Qin, Liang Guangping, Yang Zongcheng. Modification of membrane lipid of human umbilical vein endothelial cells after direct lipopolysaccharide injury. Acta Physiol Sin 2001; 53 (6): (in Chinese with English abstract).