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Ameliorative effects of adrenomedullin on rat cardiac sarcoplasmic reticulum injured by isoproterenol

Li Xianfeng, Yang Ye, Gao Lianru, Qi Yongfen, Li Zaiquan, Tang Chaoshu

Department of Cardiology,Navy General Hospital.Beijing 100037；China

Abstract

It seems that Adm exerted a protective effect on cardiac function in injured rat heart by enhancing SR Ca~(2+) uptake and release, suggesting that Adm may play a therapeutic role in myocardial injury.

Key words: Adrenomedullin;Sarcoplasmic reticulum;Ca~(2+) uptake;Ca~(2+) release;~(3)H ryanodine

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Citing This Article：

Li Xianfeng, Yang Ye, Gao Lianru, Qi Yongfen, Li Zaiquan, Tang Chaoshu. Ameliorative effects of adrenomedullin on rat cardiac sarcoplasmic reticulum injured by isoproterenol. Acta Physiol Sin 2001; 53 (5): (in Chinese with English abstract).