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5-HT_(3) receptors in amygdala mediate neuroimmunomodulation in rats

Xu Deyi, Jia Hongbin

Department of Pharmacology,School of Basic Medical Science,Southeast University.Nanjing 210009,Jiangsu

Abstract

The present study was to explore the possible immunomodulatory role of 5-HT_(3) receptors in the amygdala in rats. Concanovalin A (Con A)- and lipopolysaccharide (LPS)-stimulated splenocyte proliferation response (SPR), production of IL-2, activity of natural killer (NK) cells and serum cortisol were measured by ~(3)H-TdR incorporating method, MTT method and RIA, respectively.

Key words: Amygdala;Splenocyte proliferation response;IL-2;5-HT_(3) receptor;Neurimmunomodulation

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Citing This Article：

Xu Deyi, Jia Hongbin. 5-HT_(3) receptors in amygdala mediate neuroimmunomodulation in rats. Acta Physiol Sin 2001; 53 (5): (in Chinese with English abstract).