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Modulatory effect of orphanin FQ on the IL-1#beta# transcripts in hippocampus

Zhao Hui, Du Lina, Jiang Jianwei, Wu Gencheng, Cao Xiaoding

State Key Laboratory of Medical Neurobiology,Medical Center of Fudan University,Department of Neurobiology.Shanghai 200032

Abstract

Based on the results, we conclude that orphanin FQ functions as a neuroimmune modulator, and provokes immune response via mediationn of IL-1#beta# derived from neuron, astrocyte and microglia in hippocampus.

Key words: Orphanin FQ;Macrophage;IL-1#beta#;Neuroimrnunology;Neuron;Astrocyte

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Citing This Article：

Zhao Hui, Du Lina, Jiang Jianwei, Wu Gencheng, Cao Xiaoding. Modulatory effect of orphanin FQ on the IL-1#beta# transcripts in hippocampus. Acta Physiol Sin 2001; 53 (3): (in Chinese with English abstract).