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Therapeutic angiogenesis with the use of vascula endothelial growth factor 165 gene in the myocardium of miniature swine

Zhang Duanzhen, Gai Luyue, Chen Yiwang, Fan Ruiyun, Wen Yingfeng, Dong Wei

Department of Cardiology,the Chinese PLA General Hospital.Beijing 100853；USA

Abstract

It^s concluded that Ad-VEGF165 can induce collateral vessel development in ischemic myocardium and result in significant improvement in myocardial perfusion and function.

Key words: Endothelial growth factor;Gene therapy;Ischemic heart disease;Angiogenesis;;

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Citing This Article：

Zhang Duanzhen, Gai Luyue, Chen Yiwang, Fan Ruiyun, Wen Yingfeng, Dong Wei. Therapeutic angiogenesis with the use of vascula endothelial growth factor 165 gene in the myocardium of miniature swine. Acta Physiol Sin 2001; 53 (3): (in Chinese with English abstract).