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Hydrogen peroxide augments the injury effect of iron on the isolated rat heart and cardiomyocytes

Chen Yingying, Shen Yueliang, Cao Chunmei, Xu Wanhong, Qian Zhongming, Xia Qiang

Department of Physiology,Zhejiang University School of Medicine.Hangzhou 310006,Zhejiang；China

Abstract

It is suggested that the functional injury of sulfhydryl group containing proteins may be involved in the augmentation of myocardial injury due to the increase of intracellular iron by hydrogen peroxide, but hydroxyl radicals may not.

Key words: Iron;Head;Hydrogen peroxide

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Citing This Article：

Chen Yingying, Shen Yueliang, Cao Chunmei, Xu Wanhong, Qian Zhongming, Xia Qiang. Hydrogen peroxide augments the injury effect of iron on the isolated rat heart and cardiomyocytes. Acta Physiol Sin 2001; 53 (3): (in Chinese with English abstract).