Inhibition of ATP-activated currents by met-Enk in isolated DRG neurons of the rat
Xia Baolu, Wu Zizhen, Li Xiao, Li Qin, Li Zhiwang
Wuhan Professional Medical College.Wuhan 430016,Hubei；China
Abstract
It is suggested that the inhibition by met-Enk of I_(ATP) is caused by activation of opiate receptor, which eventually results in phosphorylation of ATP receptor, mediated by modulation of G protein coupling and intracellular signal transduction.
Key words: ATP-activated current;Met-enkephaline;Rat;DRG neuron;Inhibition;Whole-cell patch clamp technique
Received: Accepted:
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Citing This Article：
Xia Baolu, Wu Zizhen, Li Xiao, Li Qin, Li Zhiwang. Inhibition of ATP-activated currents by met-Enk in isolated DRG neurons of the rat. Acta Physiol Sin 2001; 53 (3): (in Chinese with English abstract).
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