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Relationship between heat stress suppression of neuroapoptosis and activation of nuclear kappa B in primary cultured rat cerebellar granule cells

Zheng Shuqiu, Su Xingwen, Qiu Pengxin, Chen Lijun, Wan Xiang, Yan Guangmei

Department of Pharmacology,Sun Yat-Sen University of Medical Sciences.Guangzhou 510089,Guangdong

Abstract

The results suggest that the neuroprotection of heat stress has no relation to the suppression of NF-kappa B activity, and activation of NF-kappa B may promote antiapoptotic action of heat stress.

Key words: Nuclear factor kappa B;Heat stress response;Cerebellar granule neurons;Apoptosis

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Citing This Article：

Zheng Shuqiu, Su Xingwen, Qiu Pengxin, Chen Lijun, Wan Xiang, Yan Guangmei. Relationship between heat stress suppression of neuroapoptosis and activation of nuclear kappa B in primary cultured rat cerebellar granule cells. Acta Physiol Sin 2001; 53 (3): (in Chinese with English abstract).