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Agmatine inhibits the afferent activity of carotid baroreceptor in rats

Qin Xiaomei, Fan Zhenzhong, He Ruirong

Department of Physiology,Institute of Basic Medicine,Hebei Medical University.Shijiazhuang 050017,Hebei

Abstract

These results indicate that Agm exerts an inhibitory action on carotid baroreceptor and such an action may be attributed to the reduction in calcium influx in carotid baroreceptor, which is mediated by IR and #alpha#_(2)-AR.

Key words: Agmatine;Baroreceptor activity;Carotid sinus nerve discharge;Imidazoline receptor;#alpha_(2) adrenoceptor

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Citing This Article：

Qin Xiaomei, Fan Zhenzhong, He Ruirong. Agmatine inhibits the afferent activity of carotid baroreceptor in rats. Acta Physiol Sin 2001; 53 (2): (in Chinese with English abstract).