Expression of heme oxygenase-1 in neonatal rat cardiocytes induced by lipopolysaccharide
Li Yuming, Liu Junchang, Zhang Min, Zheng Xincheng, Wu Liling, Shi Anyun, Wu Yijing
Laboratory of Hypothermic Physiology,Chengde Medical College.Chengde 067000,Hebei;China
Abstract
The results demonstrate that LPS induces HO--1 mRNA expression of NRCMs dose- and time-dependently to some extent. The inducible HO can protect NRCMs from injury and thus play an important role in pathogenesis of myocardium under LPS.
Key words: gene expression; heme oxygenase ;
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Li Yuming, Liu Junchang, Zhang Min, Zheng Xincheng, Wu Liling, Shi Anyun, Wu Yijing. Expression of heme oxygenase-1 in neonatal rat cardiocytes induced by lipopolysaccharide. Acta Physiol Sin 2001; 53 (1): (in Chinese with English abstract).