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Effect of halothane on the muscarinic potassium current of the heart

Zang Weijin, Yu Xiaojiang, Zang Yimin

Division of Cardiovascular Physiology and Pharmacology, Xi^an Medical Univesity. Xian 710061,Shaanxi；China

Abstract

Acetycholine (ACh) released from parasympathetic nerves binds to muscarinic (M2)ACh receptro (mAChR) in the heart,which leads to activation of muscarinic K~(+) channel via the #Beta# #gamma# subunit of a Gprotein

Key words: General anaesthetics;Heart;Potassium channels;Acetylcholine

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Citing This Article：

Zang Weijin, Yu Xiaojiang, Zang Yimin. Effect of halothane on the muscarinic potassium current of the heart. Acta Physiol Sin 2000; 52 (2): (in Chinese with English abstract).