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Nitric oxide inhibits the expression of proto-oncogene c-fos induced by angiotensin II and endothelin-1 in cardiomyocytes

Zhan Changde, Pan Jingyun

Key Laboratory of the Ministry of Health on Assisted Circulation,Sun Yat-sen University of Medical Sciences.Guangzhou 510089,Guangdong

Abstract

Results suggest that NO can inhibit the hypertrophic response and the proto-oncogene c-fos expression of cardiomyocytes induced by AII or ET-1 and the cross-link may be located at the site of protein kinase C.

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Citing This Article：

Zhan Changde, Pan Jingyun. Nitric oxide inhibits the expression of proto-oncogene c-fos induced by angiotensin II and endothelin-1 in cardiomyocytes. Acta Physiol Sin 2000; 52 (6): (in Chinese with English abstract).