ISSN 0371-0874, CN 31-1352/Q

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Effect of scald on gene transcription and content of endothelin-1 in supraoptic nucleus of rat hypothalamus

Jiang Yingming, Yuan Wenjun, Xiang Zhenghua, Miao Weimin, Lin Li, Li Ling, Jiao Binghua

Department of Physiology,Second Military Medical University.Shanghai 200433

Abstract

Endothelin-1 (ET-1) gene transcription and endothelin-1-immunoreactivity (ET-1-ir) in the supraoptic nucleus (SON) of rat hypothalamus were respectively observed by in situ hybridization and immunohistochemistry after scald. Intensity of ET-1 mRNA and endothelin-1-immunoreactivity (ET-1-ir) was quantified by image analysis.

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Jiang Yingming, Yuan Wenjun, Xiang Zhenghua, Miao Weimin, Lin Li, Li Ling, Jiao Binghua. Effect of scald on gene transcription and content of endothelin-1 in supraoptic nucleus of rat hypothalamus. Acta Physiol Sin 2000; 52 (5): 385-389 (in Chinese with English abstract).