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The changes in the heart and erythrocyte L-arginine transport of spontaneously hypertensive rats

Zheng Huizhen, Wang Xiaohong, Liu Xiyi, Tang Chaoshu, Liu Naikui

Department of Physiology,Guangdong Medical College.Zhanjiang 524023,Guangdong

Abstract

Changes of L-arginine/nitric oxide pathway in heart and of L-arginine transport in erythrocytes and their relationship were investigated in spontaneously hypertensive rats (SHR). The results indicate that the activity of L-arginine/nitric oxide pathway inhibited in myocardial tissue of SHR. The correlation between the inhibitory degree of L-arginine/nitric oxide pathway and the degree of ventr icular hypertrophy is negative. The changes of L-arginine transport in erythrocytes coincide with those in myocardium.

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Citing This Article：

Zheng Huizhen, Wang Xiaohong, Liu Xiyi, Tang Chaoshu, Liu Naikui. The changes in the heart and erythrocyte L-arginine transport of spontaneously hypertensive rats. Acta Physiol Sin 2000; 52 (4): (in Chinese with English abstract).