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Relationships between learning and memory and expression of nov gene of rats

Su Bingyin, Cai Wenqin, Xiong Ying, Zhang Chenggang, Perbal B

Department of Histology and Embryology,Third Military Medical University.Chongqing 400038；China；Universite Paris Ⅷ.Paris

Abstract

During the establishment of learning and memory of adult rats with active avoidance reaction expression of nov gene, nov mRNA positive neurons and NOV protein immunoreactive neurons were found in hippocampus, cingulate cortex, globus pallidus, caudate putamen and hypothalamus. The strongest positive reaction of NOV protein was observed in high ability group of learning and memory (HALM). Basic expression was found in pseudoconditioning (PC) group. The expression of NOV protein was higher in low ability group of learning and memory (LALM) than in PC group. No significant difference was detected in nov mRNA positive reaction between the three groups.

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Citing This Article：

Su Bingyin, Cai Wenqin, Xiong Ying, Zhang Chenggang, Perbal B. Relationships between learning and memory and expression of nov gene of rats. Acta Physiol Sin 2000; 52 (4): (in Chinese with English abstract).