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Basic fibroblast growth factor increases nitric oxide and endothelin production in rat aorta

Jiang Zhisheng, Yang Yongzong, Zhao Wen, Pang Yongzheng, Liu Naikui, Tang Chaoshu

Research Institute of Cardiovascular Diseases,Hengyang Medical College.Hengyang 421001,Hunan；China

Abstract

The study was undertaken to investigate the effect of basic fibroblast growth factor (bFGF) on aortic production of nitric oxide (NO) and endothelin of aorta in spontaneously hypertensive rats (SHR) and WKY rats. It is concluded that bFGF may modulate the production of NO and endothelin in both SHR and WKY rats.

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Citing This Article：

Jiang Zhisheng, Yang Yongzong, Zhao Wen, Pang Yongzheng, Liu Naikui, Tang Chaoshu. Basic fibroblast growth factor increases nitric oxide and endothelin production in rat aorta. Acta Physiol Sin 2000; 52 (3): (in Chinese with English abstract).