ISSN 0371-0874, CN 31-1352/Q

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Melatonin attenuates the intensity of #beta#-endorphin immunoreactivity in the arcuate nucleus of rat hypothalamus

Yu Changxi, Wu Gencheng, Xu Shaofen, Chen Chonghong

State Key Laboratory of Medical Neurobiology,Department of Neurobiology,Shanghai Medical University.Shanghai 200032;China

Abstract

The results suggest that melatonin may result in a decrease of #beta#-Ep content in the arcuate nucleus, as a result of increased #beta#-Ep release induced by administration of melatonin. It is likely that the analgesic effect of melatonin may be in part mediated by the release of #beta#-endorphin from the arcuate nucleus.

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Citing This Article:

Yu Changxi, Wu Gencheng, Xu Shaofen, Chen Chonghong. Melatonin attenuates the intensity of #beta#-endorphin immunoreactivity in the arcuate nucleus of rat hypothalamus. Acta Physiol Sin 2000; 52 (3): (in Chinese with English abstract).