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Effects of bFGF and BDNF on the cells of injured adult mouse olfactory epithelium in vitro

Zhang Xiaodong, Guo Zhanfang, Liu Ning, Roisen F J

Biotechnological Center,Suzhou University.Suzhou 215151,Jiangsu；USA

Abstract

The results showed that the combination of bFGF and BDNF added to 10% and 5% serum OE medium increased the bipolar cell number and percentage, stimulated the process outgrowth of bipolar cells, and decreased the numbers of giant cells and fusiform cells. The effects of the combination of bFGF and BDNF in the 10% serum OE medium were more significant than those of bFGF and BDNF applied alone; and the effects of neurotrophic factors in the 10% serum OE medium were more significant than those observed in the 5% serum OE medium.

Key words: Olfactory epithelium;Basic fibroblast growth factor;Brain derived neurotrophic factor;Immunocytochemistry

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Citing This Article：

Zhang Xiaodong, Guo Zhanfang, Liu Ning, Roisen F J. Effects of bFGF and BDNF on the cells of injured adult mouse olfactory epithelium in vitro. Acta Physiol Sin 2000; 52 (3): (in Chinese with English abstract).