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Role of nitric oxide in the reflex of raising biliary pressure

Zhang Min, Ding Chunhua, Zhang Lianwei, Yang Siyu

Department of Pathophysiology,Hebei Medical University.Shijiazhuang 050017,Hebei；China

Abstract

Raising the biliary tract pressure from the baseline to 4 kPa significantly decreases arterial blood pressure and myoelectric activity of sphincter of Oddi (SO) (bile duct-arterial blood pressure reflex), which is sometimes associated with the disappearance of phasic myoelectric activity of SO (bile duct-SO reflex). Thirty-two rabbits were used to investigate the role of nitric oxide (NO) in these reflexes. Findings suggest that both of these two reflexs are caused by the tension stimulation to the receptive area of the biliary tract, and may be mediated by NO.

Key words: Calcium;Current;Antrial circular;Smooth muscle cells;Stretch

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Citing This Article：

Zhang Min, Ding Chunhua, Zhang Lianwei, Yang Siyu. Role of nitric oxide in the reflex of raising biliary pressure. Acta Physiol Sin 2000; 52 (1): (in Chinese with English abstract).