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Simultaneous observation of parameter of intraventricular pressure and energy metabolism in rat hearts using nuclear magnetic resonance

Cheng Zengjiang, Du Zehan, Li Hongxin, Dong Huajin, Feng Rui, Li Guangyu

National Center for Biomedical Analysis,Academy of Military Medical Science.Beijing 100850；China；Institute of Pharmacolgy and Toxicology,AMMS.Beijing 100850

Abstract

A technique for simultaneous observation of parameters of intraventricular pressure and energy metabolic status in isovolumic rat hearts was described. The parameters of intraventricular pressure were collected and processed using a computerized monitoring system for heart function, and myocardial energy metabolism was investigated by collecting the ~(31)P NMR spectra. The preparation was stable metabolically and functionally for 2 h under the NMR experimental conditions.

Key words: NMR;Isolated heart;Energy metabolism

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Citing This Article：

Cheng Zengjiang, Du Zehan, Li Hongxin, Dong Huajin, Feng Rui, Li Guangyu. Simultaneous observation of parameter of intraventricular pressure and energy metabolism in rat hearts using nuclear magnetic resonance. Acta Physiol Sin 1999; 51 (6): (in Chinese with English abstract).