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Effects of intracarotid injection of capsaicin on electrical activity of rostral ventrolateral medullary neurons in rats

Xue Baojian, He Ruirong

Department of Physiology,Institute of Basic Medicine,Hebei Medical University.Shijiazhuang 050017,Hebei

Abstract

The effects of intracarotid injection of capsaicin on spontaneous electrical activity of nucleus paragigantocellularis lateralis (PGL) neurons in rostral ventrolateral medulla (RVLM) were examined in 35 anesthetized rats with sino-aortic denervation by using extracellular recording technique. Results suggest that capsaicin may stimulate the vanilloid receptor of neurons in RVLM, thereby resulting in activation of PGL neurons.

Key words: Capsaicin;Spontaneous discharge of neurons in RVLM;Capsaicin receptor;Ruthenium red

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Citing This Article：

Xue Baojian, He Ruirong. Effects of intracarotid injection of capsaicin on electrical activity of rostral ventrolateral medullary neurons in rats. Acta Physiol Sin 1999; 51 (6): (in Chinese with English abstract).